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They're not direct substitutes for each other

[HYPERPIGMENTATION CARE] Niacinamide, Pancratium Maritimum Extract, and patented BOTANLENTICAL 10 COMPLEX help visibly improve the appearance of hyperpigmentation and uneven skin texture for a more radiant, even-toned complexion

Levels decline with age and drop further in chronic disease, including Parkinson's disease, liver disease, heart disease, and alcohol use disorder